Synaptophysin antibody (N-Term) (FITC)

Catalog No. ABIN8044378

The FITC-conjugated Mouse Monoclonal anti-Synaptophysin antibody (Clone 3G12) (ABIN8044378) specifically detects Synaptophysin in FACS. The antibody is reactive with Rat and Mouse samples.

Quick Overview for Synaptophysin antibody (N-Term) (FITC) (ABIN8044378)

Target: Synaptophysin (SYP)

Reactivity: Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Synaptophysin antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: 3G12

Product Details anti-Synaptophysin Antibody (FITC)

Binding Specificity: N-Term

Purpose: Anti-SYP/Synaptophysin Antibody (monoclonal, 3G12) FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Synaptophysin, identical to the related mouse and rat sequences.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: SYP

Background:

Background: SYP (Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22). The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38 kDa. It is present inneuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).

Gene Full Name: synaptophysin

Gene ID: 6855

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity