THEM4 antibody (AA 1-240) (Biotin)

Catalog No. ABIN8046126

The Rabbit Polyclonal anti-THEM4 antibody is suitable to detect THEM4 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for THEM4 antibody (AA 1-240) (Biotin) (ABIN8046126)

Target: THEM4 (Thioesterase Superfamily Member 4 (THEM4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THEM4 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-THEM4 Antibody (Biotin)

Binding Specificity: AA 1-240

Purpose: Anti-THEM4 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human THEM4 recombinant protein (Position: M1-T240).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for THEM4

Target: THEM4 (Thioesterase Superfamily Member 4 (THEM4))

Alternative Name: THEM4

Background:

Background: Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.

Gene Full Name: thioesterase superfamily member 4

Gene ID: 117145

UniProt: Q5T1C6

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway