TXNDC3/NME8 antibody (AA 1-446) (APC)

Catalog No. ABIN8046210

The Rabbit Polyclonal anti-TXNDC3/NME8 antibody is suitable to detect TXNDC3/NME8 in samples from Human and Rat. It has been validated for FACS.

Quick Overview for TXNDC3/NME8 antibody (AA 1-446) (APC) (ABIN8046210)

Target: TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNDC3/NME8 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-TXNDC3/NME8 Antibody (APC)

Binding Specificity: AA 1-446

Purpose: Anti-TXNDC3/NME8 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TXNDC3,NME8 shares 63%,61.2% amino acid (aa) sequence identity with mouse,rat TXNDC3,NME8,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TXNDC3/NME8 recombinant protein (Position: M1-H446). Human TXNDC3/NME8 shares 63% and 61.2% amino acid (aa) sequence identity with mouse and rat TXNDC3/NME8, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TXNDC3/NME8

Target: TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))

Alternative Name: NME8

Background:

Background: This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.

Gene Full Name: NME/NM23 family member 8

Gene ID: 51314

UniProt: Q8N427

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis