TXNDC3/NME8 antibody (AA 1-446)

Catalog No. ABIN8046213

The Rabbit Polyclonal anti-TXNDC3/NME8 antibody is suitable to detect TXNDC3/NME8 in samples from Human and Rat. It has been validated for ELISA, WB and FACS.

Quick Overview for TXNDC3/NME8 antibody (AA 1-446) (ABIN8046213)

Target: TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNDC3/NME8 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-TXNDC3/NME8 Antibody

Binding Specificity: AA 1-446

Purpose: Anti-TXNDC3/NME8 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TXNDC3,NME8 shares 63%,61.2% amino acid (aa) sequence identity with mouse,rat TXNDC3,NME8,respectively.

Characteristics: Anti-TXNDC3-NME8 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TXNDC3/NME8 recombinant protein (Position: M1-H446). Human TXNDC3/NME8 shares 63% and 61.2% amino acid (aa) sequence identity with mouse and rat TXNDC3/NME8, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TXNDC3/NME8

Target: TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))

Alternative Name: NME8

Background:

Background: This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.

Gene Full Name: NME/NM23 family member 8

Molecular Weight: 67 kDa

Gene ID: 51314

UniProt: Q8N427

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis