TBXAS1 antibody (AA 157-533) (Cy3)

Catalog No. ABIN8046446

This Rabbit Polyclonal antibody specifically detects TBXAS1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TBXAS1 antibody (AA 157-533) (Cy3) (ABIN8046446)

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBXAS1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-TBXAS1 Antibody (Cy3)

Binding Specificity: AA 157-533

Purpose: Anti-TBXAS1 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TBXAS1 shares 80.6%,78.5% amino acid (aa) sequence identity with mouse,rat TBXAS1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TBXAS1 recombinant protein (Position: Q157-R533). Human TBXAS1 shares 80.6% and 78.5% amino acid (aa) sequence identity with mouse and rat TBXAS1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TBXAS1

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Alternative Name: TBXAS1

Background:

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: thromboxane A synthase 1

Gene ID: 6916

UniProt: P24557