TK1 antibody (AA 2-234) (Biotin)

Catalog No. ABIN8046489

The Rabbit Polyclonal anti-TK1 antibody is suitable to detect TK1 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for TK1 antibody (AA 2-234) (Biotin) (ABIN8046489)

Target: TK1 (Thymidine Kinase 1, Soluble (TK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TK1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TK1 Antibody (Biotin)

Binding Specificity: AA 2-234

Purpose: Anti-Thymidine Kinase 1/TK1 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human TK1 recombinant protein (Position: S2-N234). Human TK1 shares 87.1%,91.7% amino acid (aa) sequence identity with mouse,rat TK1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human TK1 recombinant protein (Position: S2-N234). Human TK1 shares 87.1% and 91.7% amino acid (aa) sequence identity with mouse and rat TK1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TK1

Target: TK1 (Thymidine Kinase 1, Soluble (TK1))

Alternative Name: TK1

Background:

Background: Thymidine kinase 1, soluble (gene name TK1), is a human thymidine kinase. Thymidine kinase catalyzes the phosphorylation of thymidine to deoxythymidine monophosphate. This gene is mapped to 17q23.2-q25.3. It is estimated that the maximal size of the TK1 gene is 14 kb and its minimal size between 4 and 5 kb. The gene contains many noncoding inserts and numerous Alu sequences. There are two forms of this protein, which have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle, it is very low in resting cells.

Gene Full Name: thymidine kinase 1

Gene ID: 7083

UniProt: P04183