TK1 antibody (AA 2-234)

Catalog No. ABIN8046499

The Rabbit Polyclonal anti-TK1 antibody (ABIN8046499) specifically detects TK1 in WB. The antibody is reactive with Human samples.

Quick Overview for TK1 antibody (AA 2-234) (ABIN8046499)

Target: TK1 (Thymidine Kinase 1, Soluble (TK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TK1 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-TK1 Antibody

Binding Specificity: AA 2-234

Purpose: Anti-Thymidine Kinase 1/TK1 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human TK1 recombinant protein (Position: S2-N234). Human TK1 shares 87.1%,91.7% amino acid (aa) sequence identity with mouse,rat TK1,respectively.

Characteristics: Anti-Thymidine Kinase 1/TK1 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human TK1 recombinant protein (Position: S2-N234). Human TK1 shares 87.1% and 91.7% amino acid (aa) sequence identity with mouse and rat TK1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TK1

Target: TK1 (Thymidine Kinase 1, Soluble (TK1))

Alternative Name: TK1

Background:

Background: Thymidine kinase 1, soluble (gene name TK1), is a human thymidine kinase. Thymidine kinase catalyzes the phosphorylation of thymidine to deoxythymidine monophosphate. This gene is mapped to 17q23.2-q25.3. It is estimated that the maximal size of the TK1 gene is 14 kb and its minimal size between 4 and 5 kb. The gene contains many noncoding inserts and numerous Alu sequences. There are two forms of this protein, which have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle, it is very low in resting cells.

Gene Full Name: thymidine kinase 1

Molecular Weight: 25 kDa

Gene ID: 7083

UniProt: P04183