TIMP3 antibody (AA 24-211) (Fluoro488)

Catalog No. ABIN8046865

The Fluoro488-conjugated Rabbit Polyclonal anti-TIMP3 antibody (ABIN8046865) specifically detects TIMP3 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TIMP3 antibody (AA 24-211) (Fluoro488) (ABIN8046865)

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMP3 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-TIMP3 Antibody (Fluoro488)

Binding Specificity: AA 24-211

Purpose: Anti-TIMP3 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human TIMP3 recombinant protein (Position: C24-P211). Human TIMP3 shares 97.9%,97.3% amino acid (aa) sequence identity with mouse,rat TIMP3,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human TIMP3 recombinant protein (Position: C24-P211). Human TIMP3 shares 97.9% and 97.3% amino acid (aa) sequence identity with mouse and rat TIMP3, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TIMP3

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Alternative Name: TIMP3

Background:

Background: Metalloproteinase inhibitor 3 is a protein that in humans is encoded by the TIMP3 gene. It is mapped to 22q12.1-q13.2. This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of theextracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

Gene Full Name: TIMP metallopeptidase inhibitor 3

Gene ID: 7078

UniProt: P35625