TLR5 antibody (AA 81-766) (Fluoro550)

Catalog No. ABIN8047394

This Rabbit Polyclonal antibody specifically detects TLR5 in FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for TLR5 antibody (AA 81-766) (Fluoro550) (ABIN8047394)

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR5 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-TLR5 Antibody (Fluoro550)

Binding Specificity: AA 81-766

Purpose: Anti-Tlr5 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Tlr5 recombinant protein (Position: Q81-D766).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TLR5

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Alternative Name: Tlr5

Background:

Background: Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. Predicted to enable interleukin-1 receptor binding activity and signaling receptor activity. Predicted to be involved in several processes, including positive regulation of interleukin-8 production, positive regulation of nitric oxide biosynthetic process, and positive regulation of toll-like receptor signaling pathway. Predicted to act upstream of or within innate immune response. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. Is expressed in brain, olfactory epithelium, spinal cord, and trunk unsegmented mesenchyme. Human ortholog(s) of this gene implicated in Legionnaires' disease, cystic fibrosis, cystitis, melioidosis, and systemic lupus erythematosus. Orthologous to human TLR5 (toll like receptor 5).

Gene Full Name: toll-like receptor 5

Gene ID: 53791

UniProt: Q9JLF7

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades