TOPBP1 antibody (AA 217-1459) (HRP)

Catalog No. ABIN8047573

The HRP-conjugated Rabbit Polyclonal anti-TOPBP1 antibody (ABIN8047573) specifically detects TOPBP1 in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TOPBP1 antibody (AA 217-1459) (HRP) (ABIN8047573)

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOPBP1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-TOPBP1 Antibody (HRP)

Binding Specificity: AA 217-1459

Purpose: Anti-TOPBP1 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TOPBP1 shares 75.3% amino acid (aa) sequence identity with mouse TOPBP1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TOPBP1 recombinant protein (Position: E217-Q1459). Human TOPBP1 shares 75.3% amino acid (aa) sequence identity with mouse TOPBP1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TOPBP1

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Alternative Name: TOPBP1

Background:

Background: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

Gene Full Name: DNA topoisomerase II binding protein 1

Gene ID: 11073

UniProt: Q92547

Pathways: Chromatin Binding