TOPBP1 antibody (AA 217-1459)

Catalog No. ABIN8047577

This Rabbit Polyclonal antibody specifically detects TOPBP1 in WB, IHC, IP, ELISA, ICC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TOPBP1 antibody (AA 217-1459) (ABIN8047577)

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOPBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-TOPBP1 Antibody

Binding Specificity: AA 217-1459

Purpose: Anti-TOPBP1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TOPBP1 shares 75.3% amino acid (aa) sequence identity with mouse TOPBP1.

Characteristics: Anti-TOPBP1 Antibody. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TOPBP1 recombinant protein (Position: E217-Q1459). Human TOPBP1 shares 75.3% amino acid (aa) sequence identity with mouse TOPBP1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TOPBP1

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Alternative Name: TOPBP1

Background:

Background: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

Gene Full Name: DNA topoisomerase II binding protein 1

Molecular Weight: 170 kDa

Gene ID: 11073

UniProt: Q92547

Pathways: Chromatin Binding