Mafg antibody (C-Term) (Cy3)

Catalog No. ABIN8048008

The Cy3-conjugated Rabbit Polyclonal anti-Mafg antibody (ABIN8048008) specifically detects Mafg in FACS. The antibody is reactive with Human samples.

Quick Overview for Mafg antibody (C-Term) (Cy3) (ABIN8048008)

Target: Mafg (Transcription Factor MafG (Mafg))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mafg antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-Mafg Antibody (Cy3)

Binding Specificity: C-Term

Purpose: Anti-MAFG Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MAFG, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Mafg

Target: Mafg (Transcription Factor MafG (Mafg))

Alternative Name: MAFG

Background:

Background: Transcription factor MafG is a bZip Maf transcription factor protein that in humans is encoded by the MAFG gene. Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877, MafG, or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).

Gene Full Name: MAF bZIP transcription factor G

Gene ID: 4097

UniProt: O15525