TMPRSS3 antibody (AA 3-454) (Fluoro594)

Catalog No. ABIN8048969

This Rabbit Polyclonal antibody specifically detects TMPRSS3 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TMPRSS3 antibody (AA 3-454) (Fluoro594) (ABIN8048969)

Target: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS3 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-TMPRSS3 Antibody (Fluoro594)

Binding Specificity: AA 3-454

Purpose: Anti-TMPRSS3 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TMPRSS3 recombinant protein (Position: E3-T454).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TMPRSS3

Target: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Alternative Name: TMPRSS3

Background:

Background: Transmembrane protease, serine 3 is an enzyme that in humans is encoded by the TMPRSS3 gene. This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.

Gene Full Name: transmembrane serine protease 3

Gene ID: 64699

UniProt: P57727

Pathways: Sensory Perception of Sound