TMPRSS6 antibody (AA 1-759) (Fluoro488)

Catalog No. ABIN8048989

The Fluoro488-conjugated Rabbit Polyclonal anti-TMPRSS6 antibody (ABIN8048989) specifically detects TMPRSS6 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TMPRSS6 antibody (AA 1-759) (Fluoro488) (ABIN8048989)

Target: TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS6 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-TMPRSS6 Antibody (Fluoro488)

Binding Specificity: AA 1-759

Purpose: Anti-Matriptase 2/TMPRSS6 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Matriptase 2/TMPRSS6 recombinant protein (Position: M1-Q759).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TMPRSS6

Target: TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))

Alternative Name: TMPRSS6

Background:

Background: Transmembrane protease, serine 6 (also known as matriptase-2) is an enzyme that in humans is encoded by the TMPRSS6 gene. The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver. Alternative splicing results in multiple transcript variants.

Gene Full Name: transmembrane serine protease 6

Gene ID: 164656

UniProt: Q8IU80

Pathways: Transition Metal Ion Homeostasis