TMEM255B antibody (AA 196-240) (Fluoro488)

Catalog No. ABIN8049144

The Rabbit Polyclonal anti-TMEM255B antibody is suitable to detect TMEM255B in samples from Mouse and Rat. It has been validated for FACS.

Quick Overview for TMEM255B antibody (AA 196-240) (Fluoro488) (ABIN8049144)

Target: TMEM255B (Transmembrane Protein 255B (TMEM255B))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM255B antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-TMEM255B Antibody (Fluoro488)

Binding Specificity: AA 196-240

Purpose: Anti-Tmem255b Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Tmem255b recombinant protein (Position: Q196-L240).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TMEM255B

Target: TMEM255B (Transmembrane Protein 255B (TMEM255B))

Alternative Name: Tmem255b

Background:

Background: FAM70B (family with sequence similarity 70, member B) is a 326 amino acid membrane protein that belongs to the FAM70 family. The gene that encodes FAM70B maps to human chromosome 13, which contains around 114 million base pairs and encodes roughly 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Gene Full Name: transmembrane protein 255B

Gene ID: 272465

UniProt: Q5FW56