Tricellulin antibody (AA 12-496) (Fluoro647)

Catalog No. ABIN8049492

The Rabbit Polyclonal anti-Tricellulin antibody is suitable to detect Tricellulin in samples from Human and Rat. It has been validated for FACS.

Quick Overview for Tricellulin antibody (AA 12-496) (Fluoro647) (ABIN8049492)

Target: Tricellulin (MARVELD2)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tricellulin antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Tricellulin Antibody (Fluoro647)

Binding Specificity: AA 12-496

Purpose: Anti-MARVELD2 Antibody Fluoro647 Conjugated

Predicted Reactivity: Human MARVELD2 shares 87% amino acid (aa) sequence identity with mouse MARVELD2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MARVELD2 recombinant protein (Position: R12-H496). Human MARVELD2 shares 87% amino acid (aa) sequence identity with mouse MARVELD2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Tricellulin

Target: Tricellulin (MARVELD2)

Alternative Name: MARVELD2

Background:

Background: MARVEL domain-containing protein 2 is a protein that in humans is encoded by the MARVELD2 gene. The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: MARVEL domain containing 2

Gene ID: 153562

UniProt: Q8N4S9

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization