TRPS1 antibody (AA 353-1257) (Fluoro647)

Catalog No. ABIN8049503

This Rabbit Polyclonal antibody specifically detects TRPS1 in FACS. It exhibits reactivity toward Human.

Quick Overview for TRPS1 antibody (AA 353-1257) (Fluoro647) (ABIN8049503)

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPS1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-TRPS1 Antibody (Fluoro647)

Binding Specificity: AA 353-1257

Purpose: Anti-TRPS1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRPS1 recombinant protein (Position: H353-D1257).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRPS1

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Alternative Name: TRPS1

Background:

Background: Zinc finger transcription factor Trps1 is a protein that in humans is encoded by the TRPS1 gene. This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III.

Gene Full Name: transcriptional repressor GATA binding 1

Gene ID: 7227

UniProt: Q9UHF7

Pathways: Protein targeting to Nucleus