TRPS1 antibody (AA 353-1257)

Catalog No. ABIN8049504

The Rabbit Polyclonal anti-TRPS1 antibody is suitable to detect TRPS1 in samples from Human. It has been validated for IHC, WB, ELISA, FACS, IF and ICC.

Quick Overview for TRPS1 antibody (AA 353-1257) (ABIN8049504)

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPS1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-TRPS1 Antibody

Binding Specificity: AA 353-1257

Purpose: Anti-TRPS1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TRPS1 Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRPS1 recombinant protein (Position: H353-D1257).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TRPS1

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Alternative Name: TRPS1

Background:

Background: Zinc finger transcription factor Trps1 is a protein that in humans is encoded by the TRPS1 gene. This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III.

Gene Full Name: transcriptional repressor GATA binding 1

Molecular Weight: 150 kDa

Gene ID: 7227

UniProt: Q9UHF7

Pathways: Protein targeting to Nucleus