TRIM24 antibody (AA 706-964) (Fluoro594)

Catalog No. ABIN8049729

The Mouse Monoclonal anti-TRIM24 antibody is suitable to detect TRIM24 in samples from Human. It has been validated for FACS.

Quick Overview for TRIM24 antibody (AA 706-964) (Fluoro594) (ABIN8049729)

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRIM24 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Clone: 4G6C2

Product Details anti-TRIM24 Antibody (Fluoro594)

Binding Specificity: AA 706-964

Purpose: Anti-TRIM24 Antibody (monoclonal, 4G6C2) Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRIM24 recombinant protein (Position: A706-D964).

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRIM24

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Alternative Name: TRIM24

Background:

Background: Tripartite motif-containing 24 (TRIM24) also known as transcriptional intermediary factor 1α (TIF1α) is a protein that, in humans, is encoded by the TRIM24 gene. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: tripartite motif containing 24

Gene ID: 8805

UniProt: O15164