TRMT1 antibody (AA 61-626) (Cy3)

Catalog No. ABIN8050091

This Rabbit Polyclonal antibody specifically detects TRMT1 in WB, ELISA, IF, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for TRMT1 antibody (AA 61-626) (Cy3) (ABIN8050091)

Target: TRMT1 (tRNA Methyltransferase 1 (TRMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMT1 antibody is conjugated to Cy3

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-TRMT1 Antibody (Cy3)

Binding Specificity: AA 61-626

Purpose: Anti-TRMT1 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRMT1 recombinant protein (Position: A61-P626).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRMT1

Target: TRMT1 (tRNA Methyltransferase 1 (TRMT1))

Alternative Name: TRMT1

Background:

Background: This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome.

Gene Full Name: tRNA methyltransferase 1

Gene ID: 55621

UniProt: Q9NXH9

Pathways: SARS-CoV-2 Protein Interactome