TRMT1 antibody (AA 61-626) (Fluoro647)

Catalog No. ABIN8050099

The Fluoro647-conjugated Rabbit Polyclonal anti-TRMT1 antibody (ABIN8050099) specifically detects TRMT1 in FACS. The antibody is reactive with Human samples.

Quick Overview for TRMT1 antibody (AA 61-626) (Fluoro647) (ABIN8050099)

Target: TRMT1 (tRNA Methyltransferase 1 (TRMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMT1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-TRMT1 Antibody (Fluoro647)

Binding Specificity: AA 61-626

Purpose: Anti-TRMT1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRMT1 recombinant protein (Position: A61-P626).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRMT1

Target: TRMT1 (tRNA Methyltransferase 1 (TRMT1))

Alternative Name: TRMT1

Background:

Background: This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome.

Gene Full Name: tRNA methyltransferase 1

Gene ID: 55621

UniProt: Q9NXH9

Pathways: SARS-CoV-2 Protein Interactome