Tryptophan Hydroxylase 1 antibody (AA 1-111) (PE)

Catalog No. ABIN8050308

The Rabbit Polyclonal anti-Tryptophan Hydroxylase 1 antibody is suitable to detect Tryptophan Hydroxylase 1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Tryptophan Hydroxylase 1 antibody (AA 1-111) (PE) (ABIN8050308)

Target: Tryptophan Hydroxylase 1 (TPH1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tryptophan Hydroxylase 1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Tryptophan Hydroxylase 1 Antibody (PE)

Binding Specificity: AA 1-111

Purpose: Anti-Tryptophan Hydroxylase/TPH1 Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Tryptophan Hydroxylase recombinant protein (Position: M1-K111).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Tryptophan Hydroxylase 1

Target: Tryptophan Hydroxylase 1 (TPH1)

Alternative Name: TPH1

Background:

Background: Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

Gene Full Name: tryptophan hydroxylase 1

Gene ID: 7166

UniProt: P17752

Pathways: Feeding Behaviour