TTL antibody (AA 104-377) (Fluoro594)

Catalog No. ABIN8050513

The Fluoro594-conjugated Rabbit Polyclonal anti-TTL antibody (ABIN8050513) specifically detects TTL in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for TTL antibody (AA 104-377) (Fluoro594) (ABIN8050513)

Target: TTL (Tubulin tyrosine Ligase (TTL))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTL antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-TTL Antibody (Fluoro594)

Binding Specificity: AA 104-377

Purpose: Anti-TTL Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TTL shares 95.3%,95.6% amino acid (aa) sequence identity with mouse,rat TTL,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TTL recombinant protein (Position: N104-L377). Human TTL shares 95.3% and 95.6% amino acid (aa) sequence identity with mouse and rat TTL, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TTL

Target: TTL (Tubulin tyrosine Ligase (TTL))

Alternative Name: TTL

Background:

Background: TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).

Gene Full Name: tubulin tyrosine ligase

Gene ID: 150465

UniProt: Q8NG68

Pathways: Regulation of Cell Size