TPCN2 antibody (AA 26-752) (Fluoro550)

Catalog No. ABIN8051757

The Rabbit Polyclonal anti-TPCN2 antibody is suitable to detect TPCN2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for TPCN2 antibody (AA 26-752) (Fluoro550) (ABIN8051757)

Target: TPCN2 (Two Pore Segment Channel 2 (TPCN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPCN2 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-TPCN2 Antibody (Fluoro550)

Binding Specificity: AA 26-752

Purpose: Anti-TPCN2 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TPCN2 shares 74.9% amino acid (aa) sequence identity with mouse TPCN2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TPCN2 recombinant protein (Position: L26-R752). Human TPCN2 shares 74.9% amino acid (aa) sequence identity with mouse TPCN2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TPCN2

Target: TPCN2 (Two Pore Segment Channel 2 (TPCN2))

Alternative Name: TPCN2

Background:

Background: This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.

Gene Full Name: two pore segment channel 2

Gene ID: 219931

UniProt: Q8NHX9