TPCN2 antibody (AA 26-752)

Catalog No. ABIN8051764

The Rabbit Polyclonal anti-TPCN2 antibody (ABIN8051764) specifically detects TPCN2 in WB, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TPCN2 antibody (AA 26-752) (ABIN8051764)

Target: TPCN2 (Two Pore Segment Channel 2 (TPCN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPCN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-TPCN2 Antibody

Binding Specificity: AA 26-752

Purpose: Anti-TPCN2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TPCN2 shares 74.9% amino acid (aa) sequence identity with mouse TPCN2.

Characteristics: Anti-TPCN2 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TPCN2 recombinant protein (Position: L26-R752). Human TPCN2 shares 74.9% amino acid (aa) sequence identity with mouse TPCN2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TPCN2

Target: TPCN2 (Two Pore Segment Channel 2 (TPCN2))

Alternative Name: TPCN2

Background:

Background: This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.

Gene Full Name: two pore segment channel 2

Molecular Weight: 95 kDa

Gene ID: 219931

UniProt: Q8NHX9