UBR2 antibody (AA 10-664) (Biotin)

Catalog No. ABIN8052052

The Biotin-conjugated Mouse Monoclonal anti-UBR2 antibody (Clone 2G10) (ABIN8052052) specifically detects UBR2 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for UBR2 antibody (AA 10-664) (Biotin) (ABIN8052052)

Target: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UBR2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 2G10

Product Details anti-UBR2 Antibody (Biotin)

Binding Specificity: AA 10-664

Purpose: Anti-UBR2 Antibody (monoclonal, 2G10) Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human UBR2 recombinant protein (Position: Q10-A664).

Isotype: IgG2a

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for UBR2

Target: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Alternative Name: UBR2

Background:

Background: E3 ubiquitin-protein ligase UBR2 is an enzyme that in humans is encoded by the UBR2 gene. It is mapped to 6p21.1. This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.

Gene Full Name: ubiquitin protein ligase E3 component n-recognin 2

Gene ID: 23304

UniProt: Q8IWV8