VEGFC antibody (AA 108-223) (APC)

Catalog No. ABIN8053485

The Rabbit Polyclonal anti-VEGFC antibody is suitable to detect VEGFC in samples from Mouse and Rat. It has been validated for FACS.

Quick Overview for VEGFC antibody (AA 108-223) (APC) (ABIN8053485)

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFC antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-VEGFC Antibody (APC)

Binding Specificity: AA 108-223

Purpose: Anti-Vegfc Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Vegfc recombinant protein (Position: A108-R223).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for VEGFC

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Alternative Name: Vegfc

Background:

Background: Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family. It is encoded in humans by the VEGFC gene, which is located on chromosome 4q34. Enables vascular endothelial growth factor receptor 3 binding activity. Involved in several processes, including negative regulation of osteoblast differentiation, positive regulation of angiogenesis, and positive regulation of mesenchymal stem cell proliferation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor, positive regulation of lymphangiogenesis, and positive regulation of peptidyl-tyrosine phosphorylation. Located in extracellular space. Is expressed in several structures, including alimentary system mesentery, brain, cardiovascular system, embryo mesenchyme, and genitourinary system. Used to study hereditary lymphedema. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Orthologous to human VEGFC (vascular endothelial growth factor C).

Gene Full Name: vascular endothelial growth factor C

Gene ID: 22341

UniProt: P97953

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2