VWF antibody (AA 1304-1452) (Fluoro488)

Catalog No. ABIN8053832

This Rabbit Polyclonal antibody specifically detects VWF in FACS. It exhibits reactivity toward Rat and Mouse.

Quick Overview for VWF antibody (AA 1304-1452) (Fluoro488) (ABIN8053832)

Target: VWF (Von Willebrand Factor (VWF))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VWF antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-VWF Antibody (Fluoro488)

Binding Specificity: AA 1304-1452

Purpose: Anti-Von Willebrand Factor/VWF Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse VWF recombinant protein (Position: M1304-E1452).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for VWF

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: VWF

Background:

Background: Von Willebrand factor (VWF) is a blood glycoprotein involved in hemostasis. It is mapped to 12p13.31. The VWF gene encodes von Willebrand factor (VWF), a large multimeric glycoprotein that plays a central role in the blood coagulation system, serving both as a major mediator of platelet-vessel wall interaction and platelet adhesion, and as a carrier for coagulation factor VIII. VWF released from endothelial cell Weibel-Palade bodies bound particularly avidly to the extracellular matrix. VWF deficiency or dysfunction (von Willebrand disease) leads to a bleeding tendency, which is most apparent in tissues having high blood flow shear in narrow vessels.

Gene Full Name: Von Willebrand factor

Sequence Similarities: Contains 1 CTCK (C-terminal cystine knot-like) domain.

Gene ID: 22371

UniProt: Q8CIZ8