VWF antibody (AA 1304-1452)

Catalog No. ABIN8053840

The Rabbit Polyclonal anti-VWF antibody (ABIN8053840) specifically detects VWF in IHC, WB and IF. The antibody is reactive with Rat and Mouse samples.

Quick Overview for VWF antibody (AA 1304-1452) (ABIN8053840)

Target: VWF (Von Willebrand Factor (VWF))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VWF antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-VWF Antibody

Binding Specificity: AA 1304-1452

Purpose: Anti-Von Willebrand Factor/VWF Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Von Willebrand Factor/VWF Antibody. Tested in IF, IHC, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse VWF recombinant protein (Position: M1304-E1452).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat Immunofluorescence, 2 μg/mL, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for VWF

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: VWF

Background:

Background: Von Willebrand factor (VWF) is a blood glycoprotein involved in hemostasis. It is mapped to 12p13.31. The VWF gene encodes von Willebrand factor (VWF), a large multimeric glycoprotein that plays a central role in the blood coagulation system, serving both as a major mediator of platelet-vessel wall interaction and platelet adhesion, and as a carrier for coagulation factor VIII. VWF released from endothelial cell Weibel-Palade bodies bound particularly avidly to the extracellular matrix. VWF deficiency or dysfunction (von Willebrand disease) leads to a bleeding tendency, which is most apparent in tissues having high blood flow shear in narrow vessels.

Gene Full Name: Von Willebrand factor

Sequence Similarities: Contains 1 CTCK (C-terminal cystine knot-like) domain.

Molecular Weight: 309 kDa

Gene ID: 22371

UniProt: Q8CIZ8