VWF antibody (AA 2535-2813) (HRP)

Catalog No. ABIN8053858

The HRP-conjugated Rabbit Polyclonal anti-VWF antibody (ABIN8053858) specifically detects VWF in IHC, WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for VWF antibody (AA 2535-2813) (HRP) (ABIN8053858)

Target: VWF (Von Willebrand Factor (VWF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VWF antibody is conjugated to HRP

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-VWF Antibody (HRP)

Binding Specificity: AA 2535-2813

Purpose: Anti-Von Willebrand Factor/VWF Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human VWF shares 79% amino acid (aa) sequence identity with mouse VWF.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human VWF recombinant protein (Position: R2535-K2813). Human VWF shares 79% amino acid (aa) sequence identity with mouse VWF.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for VWF

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: VWF

Background:

Background: Von Willebrand factor (VWF) is a blood glycoprotein involved in hemostasis. It is mapped to 12p13.31. The VWF gene encodes von Willebrand factor (VWF), a large multimeric glycoprotein that plays a central role in the blood coagulation system, serving both as a major mediator of platelet-vessel wall interaction and platelet adhesion, and as a carrier for coagulation factor VIII. VWF released from endothelial cell Weibel-Palade bodies bound particularly avidly to the extracellular matrix. VWF deficiency or dysfunction (von Willebrand disease) leads to a bleeding tendency, which is most apparent in tissues having high blood flow shear in narrow vessels.

Gene Full Name: von Willebrand factor

Sequence Similarities: Contains 1 CTCK (C-terminal cystine knot-like) domain.

Gene ID: 7450

UniProt: P04275