WAPAL antibody (AA 916-1190) (APC)

Catalog No. ABIN8054410

The APC-conjugated Rabbit Polyclonal anti-WAPAL antibody (ABIN8054410) specifically detects WAPAL in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for WAPAL antibody (AA 916-1190) (APC) (ABIN8054410)

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WAPAL antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-WAPAL Antibody (APC)

Binding Specificity: AA 916-1190

Purpose: Anti-WAPL/FOE Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human WAPL/FOE recombinant protein (Position: Q916-C1190).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for WAPAL

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Alternative Name: WAPL

Background:

Background: WAPL (wings apart-like), also known as WAPAL or FOE, is a 1,190 amino acid protein that contains one WAPL domain and may play an important role in cell growth. It is expressed in an isoform dependent manner in heart, skeletal muscle (isoform 2) and uterine cervix tumor tissue (isoform 1). WAPL is involved in sister-chromatid adhesion and promotes release of cohesin from chromosomes by ly interacting with its regulatory subunits. WAPL is a new regulator of the development and metastasis of cancerous tissue.

Gene Full Name: WAPL cohesin release factor

Gene ID: 23063

UniProt: Q7Z5K2

Pathways: Chromatin Binding