WAPAL antibody (AA 916-1190)

Catalog No. ABIN8054413

The Rabbit Polyclonal anti-WAPAL antibody (ABIN8054413) specifically detects WAPAL in WB, ELISA, IF, FACS, ICC and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for WAPAL antibody (AA 916-1190) (ABIN8054413)

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WAPAL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-WAPAL Antibody

Binding Specificity: AA 916-1190

Purpose: Anti-WAPL/FOE Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-WAPL/FOE Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human WAPL/FOE recombinant protein (Position: Q916-C1190).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for WAPAL

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Alternative Name: WAPL

Background:

Background: WAPL (wings apart-like), also known as WAPAL or FOE, is a 1,190 amino acid protein that contains one WAPL domain and may play an important role in cell growth. It is expressed in an isoform dependent manner in heart, skeletal muscle (isoform 2) and uterine cervix tumor tissue (isoform 1). WAPL is involved in sister-chromatid adhesion and promotes release of cohesin from chromosomes by ly interacting with its regulatory subunits. WAPL is a new regulator of the development and metastasis of cancerous tissue.

Gene Full Name: WAPL cohesin release factor

Molecular Weight: 180 kDa

Gene ID: 23063

UniProt: Q7Z5K2

Pathways: Chromatin Binding