YBX1 antibody (Middle Region) (PE)

Catalog No. ABIN8054863

The PE-conjugated Rabbit Polyclonal anti-YBX1 antibody (ABIN8054863) specifically detects YBX1 in FACS. The antibody is reactive with Rat and Mouse samples.

Quick Overview for YBX1 antibody (Middle Region) (PE) (ABIN8054863)

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YBX1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-YBX1 Antibody (PE)

Binding Specificity: Middle Region

Purpose: Anti-YB1/Ybx1 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse YB1/Ybx1, identical to the related rat sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for YBX1

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Alternative Name: Ybx1

Background:

Background: Y box binding protein 1 also known as Y-box transcription factor or nuclease-sensitive element-binding protein 1 is a protein that in humans is encoded by the YBX1 gene. Enables chromatin binding activity, mRNA binding activity, and single-stranded DNA binding activity. Involved in epidermis development and negative regulation of cellular senescence. Acts upstream of or within several processes, including cellular response to interleukin-7, negative regulation of striated muscle cell differentiation, and negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of histone pre-mRNA 3'end processing complex. Is expressed in several structures, including branchial arch, central nervous system, facial prominence, gonad, and retina. Orthologous to human YBX1 (Y-box binding protein 1).

Gene Full Name: Y box protein 1

Gene ID: 22608

UniProt: P62960

Pathways: Regulation of Muscle Cell Differentiation