Collagen Type V antibody

Catalog No. ABIN8065430

This Mouse Monoclonal antibody specifically detects Collagen Type V in WB, ELISA and IHC. It exhibits reactivity toward Dog.

Quick Overview for Collagen Type V antibody (ABIN8065430)

Target: Collagen Type V (COL5) (Collagen, Type V (COL5))

Reactivity: Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This Collagen Type V antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Grade: Carrier-free

Clone: 1E2-E4-Col5

Product Details anti-Collagen Type V Antibody

Purpose: Anti-Type V Collagen Antibody

Specificity: CSI 006-01 is highly specific for type V collagen. It has been shown to have no cross-reactivity with type I, III and VI collagens by ELISA and immunoblotting. There is no evidence for cross-reactivity with other connective tissue proteins (laminin, fibronectin, elastin).

Predicted Reactivity: Bovine,Canine,Human,Kangaroo,Pig,Rabbit,and Sheep (ovine)

Purification: Protein A or Protein G purified

Immunogen: Acid-digested pepsin soluble dog type V collagen

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C without exposure to light

Expiry Date: 24 months

Target Details for Collagen Type V

Target: Collagen Type V (COL5) (Collagen, Type V (COL5))

Alternative Name: Type V Collagen

Background: COL5A1, EDSC, EDSCL1, FMDMF, collagen alpha-1(V) chain, collagen, type V, alpha 1,Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.,COL5A1,Type V collagen is a minor component of the connective tissue, although it is present in many different types of connective tissue. Patients with defects in the type V collagen (Ehlers-Danlos syndrome) have weakend connective tissue characterized by hyperstrechable joints and fragile, easily bruisable skin.

Molecular Weight: 184 kDa

Gene ID: 1289

UniProt: A0A8I3NPQ5