PPY antibody

Catalog No. ABIN8065515

The Mouse Monoclonal anti-PPY antibody is suitable to detect PPY in samples from Human. It has been validated for WB and ELISA.

Quick Overview for PPY antibody (ABIN8065515)

Target: PPY (Pancreatic Polypeptide (PPY))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPY antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Clone: 6

Product Details anti-PPY Antibody

Purpose: Anti-Pancreatic Polypeptide Antibody

Specificity: ABS 030-06 binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1 % .

Predicted Reactivity: Human

Purification: Protein A or Protein G purified

Immunogen: Synthetic human PP

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C without exposure to light

Expiry Date: 24 months

Target Details for PPY

Target: PPY (Pancreatic Polypeptide (PPY))

Alternative Name: Pancreatic Polypeptide

Background: PPY, PH, PNP, PP, pancreatic polypeptide prohormone, pancreatic polypeptide Y, pancreatic prohormone, prepro-PP (prepropancreatic polypeptide),[Pancreatic polypeptide]: Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2. {ECO:0000269|PubMed:7493937, ECO:0000269|PubMed:7592911}.,PPY,Pancreatic polypeptide (PP) is a 36 amino acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.

Molecular Weight: 10 kDa

Gene ID: 5539

UniProt: P01298

Pathways: Feeding Behaviour