Procollagen Type I Propeptide antibody (C-Term)

Catalog No. ABIN8065524

The Mouse Monoclonal anti-Procollagen Type I Propeptide antibody is suitable to detect Procollagen Type I Propeptide in samples from Human. It has been validated for ELISA.

Quick Overview for Procollagen Type I Propeptide antibody (C-Term) (ABIN8065524)

Target: Procollagen Type I Propeptide

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Procollagen Type I Propeptide antibody is un-conjugated

Application: ELISA

Grade: Carrier-free

Clone: 4

Product Details anti-Procollagen Type I Propeptide Antibody

Binding Specificity: C-Term

Purpose: Anti-Procollagen Type I C-terminal Propeptide (PICP) Antibody

Specificity: BTE 002-04 is specific for for native PICP from amniotic fluid.

Predicted Reactivity: Human

Purification: Protein A or Protein G purified

Immunogen: PICP purified from second trimester amniotic fluid by affinity chromatography

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C without exposure to light

Expiry Date: 24 months

Target Details for Procollagen Type I Propeptide

Target: Procollagen Type I Propeptide

Background: COL1A1, CAFYD, EDSARTH1, EDSC, OI1, OI2, OI3, OI4, collagen alpha-1(I) chain, alpha-1 type I collagen, alpha1(I) procollagen, collagen Col1-ColIII-1, collagen Col1-ColIII-2, collagen alpha 1 chain type I, collagen alpha-1(I) chain preproprotein, collagen of skin, tendon and bone, alpha-1 chain, collagen, type I, alpha 1, pro-alpha-1 collagen type 1, type I proalpha 1, type I procollagen alpha 1 chain,Type I collagen is a member of group I collagen (fibrillar forming collagen).,COL1A1,Collagen type I is present in soft connective tissue and bone where it represents approximately 90 % of the organic matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the precursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100 kDa and the normal range in serum is 100-300 μg/mL.

Molecular Weight: 100 kDa (native trimeric), 35 kDa (monomer)

Gene ID: 1277

UniProt: P02452