Vitronectin antibody

Catalog No. ABIN8065533

The Human Monoclonal anti-Vitronectin antibody is suitable to detect Vitronectin in samples from Human. It has been validated for WB, IHC, ELISA and AP.

Quick Overview for Vitronectin antibody (ABIN8065533)

Target: Vitronectin (VTN)

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This Vitronectin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Affinity Purification (AP)

Grade: Carrier-free

Clone: HV2

Product Details anti-Vitronectin Antibody

Purpose: Anti-Vitronectin Antibody

Specificity: Vitronectin (human). The epitope is located in the connecting region. Binding can be competed selectively by a peptide comprising aa 121-133.

Predicted Reactivity: Human

Purification: Protein A or Protein G purified

Immunogen: Human vitronectin purified from plasma by heparin-affinity chromatography

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C without exposure to light

Expiry Date: 24 months

Target Details for Vitronectin

Target: Vitronectin (VTN)

Alternative Name: Vitronectin

Background: VTN, V75, VN, VNT, vitronectin, complement S-protein, epibolin, serum spreading factor, somatomedin B,Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway., Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.,VTN,Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognizes fibronectin. (2)

Molecular Weight: 65 kDa, 75 kDA

Gene ID: 7448

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration