DNMT1 antibody (pTyr399) (Biotin)

Catalog No. ABIN757749

This anti-DNMT1 antibody is a Rabbit Polyclonal antibody detecting DNMT1 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for DNMT1 antibody (pTyr399) (Biotin) (ABIN757749)

Target: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNMT1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DNMT1 Antibody (Biotin)

Binding Specificity: pTyr399

Predicted Reactivity: Human,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Dnmt1 around the phosphorylation site of Tyr399

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for DNMT1

Target: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Alternative Name: Dnmt1

Background:

Synonyms: Dnmt1phospho Y399, Dnmt1 phospho Tyr399, p-Dnmt1 Tyr399, AIM, CXXC finger protein 9, CXXC-type zinc finger protein 9, CXXC9, DNA cytosine 5 methyltransferase 1, DNA cytosine-5-methyltransferase 1, DNA methyltransferase 1, DNA methyltransferase HsaI, DNA methyltransferase M.HsaI., DNA MTase, DNA MTase HsaI, DNMT 1, DNMT, Dnmt1, Dnmt1, DNMT1_HUMAN, Dnmt1o, FLJ16293, HSN1E, M.HsaI, MCMT, Met1, MGC104992, mMmul, MommeD2.

Background: DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

Gene ID: 1786

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection