CEBPZ antibody (N-Term)

Catalog No. ABIN8096442

The Rabbit Polyclonal anti-CEBPZ antibody (ABIN8096442) specifically detects CEBPZ in WB. The antibody is reactive with Human samples.

Quick Overview for CEBPZ antibody (N-Term) (ABIN8096442)

Target: CEBPZ (CCAAT/enhancer Binding Protein (C/EBP), zeta (CEBPZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEBPZ antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CEBPZ Antibody

Binding Specificity: N-Term

Purpose: CEBPZ Antibody - N-terminal region

Sequence: MAAVKEPLEF HAKRPWRPEE AVEDPDEEDE DNTSEAENGF SLEEVLRLGG

Predicted Reactivity: Cow: 77%, Horse: 80%, Human: 100%, Mouse: 80%, Pig: 77%, Rabbit: 85%, Rat: 82%, Yeast: 83%, Zebrafish: 83%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPZ

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38679-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CEBPZ

Target: CEBPZ (CCAAT/enhancer Binding Protein (C/EBP), zeta (CEBPZ))

Alternative Name: CEBPZ

Background:

Background Information: This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML).

Gene Name: CCAAT enhancer binding protein zeta

Alternative Symbols: CBF, CBF2, NOC1, HSP-CBF

Protein Name: CCAAT/enhancer-binding protein zeta

Molecular Weight: 115 kDa

Gene ID: 10153

NCBI Accession: NP_005751

UniProt: Q03701