CHSY1 antibody (C-Term)

Catalog No. ABIN8096980

This Rabbit Polyclonal antibody specifically detects CHSY1 in WB. It exhibits reactivity toward Human.

Quick Overview for CHSY1 antibody (C-Term) (ABIN8096980)

Target: CHSY1 (Chondroitin Sulfate Synthase 1 (CHSY1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHSY1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHSY1 Antibody

Binding Specificity: C-Term

Purpose: CHSY1 Antibody - C-terminal region

Sequence: CDPNLDPKQY KMCLGSKAST YGSTQQLAEM WLEKNDPSYS KSSNNNGSVR

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CHSS1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73930-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHSY1

Target: CHSY1 (Chondroitin Sulfate Synthase 1 (CHSY1))

Alternative Name: CHSY1

Background:

Background Information: This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome.

Gene Name: chondroitin sulfate synthase 1

Alternative Symbols: CHSY, CSS1, TPBS, ChSy-1

Protein Name: chondroitin sulfate synthase 1

Molecular Weight: 88kDa

Gene ID: 22856

NCBI Accession: NP_055733

UniProt: Q86X52

Pathways: Glycosaminoglycan Metabolic Process