DDX10 antibody (C-Term)

Catalog No. ABIN8098590

The Rabbit Polyclonal anti-DDX10 antibody (ABIN8098590) specifically detects DDX10 in WB. The antibody is reactive with Human samples.

Quick Overview for DDX10 antibody (C-Term) (ABIN8098590)

Target: DDX10 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 10 (DDX10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DDX10 Antibody

Binding Specificity: C-Term

Purpose: DDX10 Antibody - C-terminal region

Sequence: EANKRQAKAK DEEEAFLDWS DDDDDDDDGF DPSTLPDPDK YRSSEDSDSE

Predicted Reactivity: Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DDX10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36369-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DDX10

Target: DDX10 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 10 (DDX10))

Alternative Name: DDX10

Background:

Background Information: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies.  

Gene Name: DEAD-box helicase 10

Alternative Symbols: Dbp4, HRH-J8

Protein Name: probable ATP-dependent RNA helicase DDX10

Molecular Weight: 96 kDa

Gene ID: 1662

NCBI Accession: NP_004389

UniProt: Q13206

Pathways: SARS-CoV-2 Protein Interactome