DIS3L antibody (C-Term)

Catalog No. ABIN8098958

The Rabbit Polyclonal anti-DIS3L antibody is suitable to detect DIS3L in samples from Human. It has been validated for WB.

Quick Overview for DIS3L antibody (C-Term) (ABIN8098958)

Target: DIS3L (DIS3-Like Exonuclease 1 (DIS3L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIS3L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DIS3L Antibody

Binding Specificity: C-Term

Purpose: DIS3L Antibody - C-terminal region

Sequence: NNRNQAAQHS QKQSTELFQC MYFKDKDPAT EERCISDGVI YSIRTNGVLL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rat: 93%, Zebrafish: 85%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DIS3L

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41096-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DIS3L

Target: DIS3L (DIS3-Like Exonuclease 1 (DIS3L))

Alternative Name: DIS3L

Background:

Background Information: The cytoplasmic RNA exosome complex degrades unstable mRNAs and is involved in the regular turnover of other mRNAs. The protein encoded by this gene contains 3'-5' exoribonuclease activity and is a catalytic component of this complex.  

Gene Name: DIS3 like exosome 3'-5' exoribonuclease

Alternative Symbols: DIS3L1

Protein Name: DIS3-like exonuclease 1

Molecular Weight: 115 kDa

Gene ID: 115752

NCBI Accession: NP_588616

UniProt: Q8TF46