ENPP2 antibody (N-Term)

Catalog No. ABIN8099461

This Rabbit Polyclonal antibody specifically detects ENPP2 in WB. It exhibits reactivity toward Human.

Quick Overview for ENPP2 antibody (N-Term) (ABIN8099461)

Target: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ENPP2 Antibody

Binding Specificity: N-Term

Purpose: ENPP2 Antibody - N-terminal region

Sequence: QWLTLPDHER PSVYAFYSEQ PDFSGHKYGP FGPEMTNPLR EIDKIVGQLM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ENPP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44908-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Alternative Name: ENPP2

Background:

Background Information: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: ectonucleotide pyrophosphatase/phosphodiesterase 2

Alternative Symbols: ATX, NPP2, ATX-X, PDNP2, LysoPLD, AUTOTAXIN, PD-IALPHA

Protein Name: ectonucleotide pyrophosphatase/phosphodiesterase family member 2

Molecular Weight: 100 kDa

Gene ID: 5168

NCBI Accession: NP_001035181

UniProt: Q13822