FTO antibody (AA 328-505)

Catalog No. ABIN8100502

This Rabbit Polyclonal antibody specifically detects FTO in WB. It exhibits reactivity toward Human.

Quick Overview for FTO antibody (AA 328-505) (ABIN8100502)

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTO antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FTO Antibody

Binding Specificity: AA 328-505

Purpose: FTO Polyclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant Human FTO aa 328-505

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FTO

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Alternative Name: FTO

Background:

Background Information: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]

Gene Name: Fat mass and obesity associated

Alternative Symbols: GDFD, ALKBH9, BMIQ14

Protein Name: Alpha-ketoglutarate-dependent dioxygenase FTO

Molecular Weight: 58 kDa

Gene ID: 79068

NCBI Accession: NP_001073901

UniProt: Q9C0B1