Glutathione Synthetase antibody (C-Term)

Catalog No. ABIN8101702

This Rabbit Polyclonal antibody specifically detects Glutathione Synthetase in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio), Goat and Saccharomyces cerevisiae.

Quick Overview for Glutathione Synthetase antibody (C-Term) (ABIN8101702)

Target: Glutathione Synthetase (GSS)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio), Goat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Synthetase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glutathione Synthetase Antibody

Binding Specificity: C-Term

Purpose: GSS Antibody - C-terminal region

Sequence: FRDGYMPRQY SLQNWEARLL LERSHAAKCP DIATQLAGTK KVQQELSRPG

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 75%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 86%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GSHB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54302-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Glutathione Synthetase

Target: Glutathione Synthetase (GSS)

Alternative Name: GSS

Background:

Background Information: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Gene Name: glutathione synthetase

Alternative Symbols: GSHS, HEL-S-64p, HEL-S-88n

Protein Name: glutathione synthetase

Molecular Weight: 52kDa

Gene ID: 2937

NCBI Accession: XP_005260463

UniProt: P48637

Pathways: Warburg Effect