HECTD3 antibody (Middle Region)

Catalog No. ABIN8102307

The Rabbit Polyclonal anti-HECTD3 antibody (ABIN8102307) specifically detects HECTD3 in WB. The antibody is reactive with Human samples.

Quick Overview for HECTD3 antibody (Middle Region) (ABIN8102307)

Target: HECTD3 (HECT Domain Containing 3 (HECTD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HECTD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HECTD3 Antibody

Binding Specificity: Middle Region

Purpose: HECTD3 Antibody - middle region

Sequence: TDDNFMPKRV VVYGGEGDNL KKLSDVSIDE TLIGDVCVLE DMTVHLPIIE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the Middle region of human HECTD3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43316-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HECTD3

Target: HECTD3 (HECT Domain Containing 3 (HECTD3))

Alternative Name: HECTD3

Background:

Background Information: The protein encoded by this gene transfers ubiquitin from an E2 ubiquitin-conjugating enzyme to targeted substrates, leading to the degradation of those substrates. The encoded protein has been shown to transfer ubiquitin to TRIOBP to facilitate cell cycle progression, and to STX8.

Gene Name: HECT domain containing E3 ubiquitin protein ligase 3

Protein Name: E3 ubiquitin-protein ligase HECTD3

Molecular Weight: 97 kDa

Gene ID: 79654

NCBI Accession: NP_078878

UniProt: Q5T447