NDUFA13 antibody (N-Term)

Catalog No. ABIN8106143

The Rabbit Polyclonal anti-NDUFA13 antibody is suitable to detect NDUFA13 in samples from Human. It has been validated for WB.

Quick Overview for NDUFA13 antibody (N-Term) (ABIN8106143)

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFA13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NDUFA13 Antibody

Binding Specificity: N-Term

Purpose: NDUFA13 Antibody - N-terminal region

Sequence: MPPPGGYGPI DYKRNLPRRG LSGYSMLAIG IGTLIYGHWS IMKWNRERRR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NDUAD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75565-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Alternative Name: NDUFA13

Background:

Background Information: This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.

Gene Name: NADH:ubiquinone oxidoreductase subunit A13

Alternative Symbols: B16.6, CDA016, CGI-39, GRIM19, GRIM-19, MC1DN28

Protein Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

Molecular Weight: 15kDa

Gene ID: 51079

NCBI Accession: NP_057049

UniProt: Q9P0J0

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling