Recombinant CD74 antibody (Lumenal Loop)

Catalog No. ABIN8117726

The Rabbit Chimeric anti-CD74 antibody is suitable to detect CD74 in samples from Human. It has been validated for FACS, WB, IF, IP, RIA, in vitro and LCI.

Quick Overview for Recombinant CD74 antibody (Lumenal Loop) (ABIN8117726)

Target: CD74 (HLA-DR-gamma (CD74))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CD74 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Radioimmunoassay (RIA), In vitro Assay (in vitro), Live Cell Imaging (LCI)

Grade: Carrier-free

Clone: BU45

Product Details anti-CD74 Antibody

Binding Specificity: Lumenal Loop

Purpose: CD74 [BU45], Rabbit IgG, Recombinant Monoclonal Antibody: Low Endotoxin- Preservative-Free

Specificity: This antibody is specific for the lumenal portion of human CD74.

Purification: Protein A affinity purified

Endotoxin Level: Low Endotoxin

Immunogen: The original antibody was raised by immunizing a mouse with B lymphoblastoid cell line, HFBl.

Isotype: IgG

Application Details

Application Notes: Optimal antibody dilution should be determined by user laboratory since it may be dependent on the detection system.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Preservative: Without preservative

Target Details for CD74

Target: CD74 (HLA-DR-gamma (CD74))

Alternative Name: CD74

Background: Li, Ia antigen-associated invariant chain, HLA-DR antigens-associated invariant chain, HLA class II histocompatibility antigen gamma chain, invariant chain

UniProt: P04233

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints