GADD45GIP1 antibody (AA 121-222)

Catalog No. ABIN761096

The Rabbit Polyclonal anti-GADD45GIP1 antibody is suitable to detect GADD45GIP1 in samples from Human. It has been validated for ELISA, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for GADD45GIP1 antibody (AA 121-222) (ABIN761096)

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD45GIP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GADD45GIP1 Antibody

Binding Specificity: AA 121-222

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GADD45GIP1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GADD45GIP1

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Alternative Name: Gadd45gip1

Background:

Synonyms: CKBBP2, CKII beta associating protein, CKII beta binding protein 2, CKII beta-associating protein, CR6 interacting factor 1, CR6-interacting factor 1, CR1, G45IP_HUMAN, Gadd45gip1, growth arrest and DNA damage inducible, gamma interacting protein 1, Growth arrest and DNA damage-inducible proteins-interacting protein 1, p53 responsive gene 6, p53 responsive gene 6 protein, p53-responsive gene 6 protein, Papillomavirus L2 interacting nuclear protein 1, Papillomavirus L2-interacting nuclear protein 1, PLINP 1, PLINP-1, PLINP1, PRG6.

Background: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.

Gene ID: 90480