ADAM10 antibody (AA 170-250)

Catalog No. ABIN8119565

This Rabbit Polyclonal antibody specifically detects ADAM10 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ADAM10 antibody (AA 170-250) (ABIN8119565)

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADAM10 Antibody

Binding Specificity: AA 170-250

Purpose: ADAM10 Antibody

Specificity: ADAM10 Polyclonal Antibody detects endogenous levels of ADAM10 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from ADAM10 . at AA range: 170-250

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ADAM10

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Alternative Name: ADAM10

Background:

Synonyms: ADAM10, KUZ, MADM, Disintegrin and metalloproteinase domain-containing protein 10, ADAM 10, CDw156, Kuzbanian protein homolog, Mammalian disintegrin-metalloprotease, CD antigen CD156c

Background: ADAM metallopeptidase domain 10(ADAM10) Homo sapiens Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains.This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016],

Gene Name: ADAM10

Protein Name: Disintegrin and metalloproteinase domain-containing protein 10

Gene ID: 102

UniProt: O14672

Pathways: Notch Signaling, EGFR Signaling Pathway